教师详情-凯发k8娱乐

1. 2018年，兰州大学“双一流”引导专项-科研启动费，70万，主持

2. 2019年教育部逆境重点实验室项目lzujbky-2019-kb05，利用快中子诱导的蒺藜苜蓿突变体库对豆科植物共生固氮缺失突变体的筛选和生物学鉴定，主持

3. 2021年教育部逆境重点实验室项目lzujbky-2021-kb05，蒺藜苜蓿tml基因调控根瘤发育的研究，主持

4. 2021年中央高校交叉学科创新群体项目lzujbky-2021-ct14，牧草抗逆基因资源挖掘与利用创新团队，参与

5. 2023年教育部逆境重点实验室项目lzujbky-2022-kb03，蒺藜苜蓿pif基因家族的生物信息学分析，主持

1. 指导研究生6名：已毕业3名，在读3名

2. 本科生教学(undergraduate teaching):

主讲本科生课程：生物化学与分子生物学、生物化学与分子生物学实验、生物化学实验

3. 研究生教学(postgraduate teaching):

主讲研究生课程：论文写作指导与专业英语

4. 课程建设：

《生物化学实验》，2022年甘肃省一流课程（线上线下混合式）

《生物化学实验》，2023年国家级一流课程（线上线下混合式）

5. 教材建设：

《生物化学实验》参编

研究方向：

1.豆科植物共生固氮机理及其应用的研究。

2.豆科植物生长发育调控的研究。

1. 2021年获生命科学学院大学生创新创业训练项目优秀指导老师称号

2. 2022年获得生命科学学院学生评选的”最暖宿舍导师奖“

3. 2022年甘肃省大学生生命科学大赛二等奖

4. 2022年全国大学生生命科学大赛三等奖

5. 2023年获兰州大学本科毕业论文（设计）优秀指导教师

1.         fengzhan gao, jian yang, niu zhai, chao zhang, xinru ren, yating zeng, yuhui chen, rujin chen, huairong pan. ncr343 is required to maintain the viability of differentiated bacteroids in nodule cells in medicago truncatula. new phytol. jul, 13, 2023, accepted.

2.         jian yang , niu zhai , yuhui chen , luying wang , rujin chen, huairong pan. a signal peptide peptidase is required for er-symbiosome proximal association and protein secretion. nature communications, jul, 9, 2023. accepted.

3.         shen y, ma y, li d, kang m, pei y, zhang r, tao w, huang s, song w, li y, huang w, wang d and chen y*. biological and genomic analysis of a symbiotic nitrogen fixation defective mutant in medicago truncatula. front. plant sci. 2023, 14:1209664. doi: 10.3389/fpls.2023.1209664

4.         horváth b, güngör b, tóth m, domonkos á, ayaydin f, saifi f, chen y, biró jb, bourge m, szabó z, tóth z, chen r, kaló p. the medicago truncatula nodule-specific cysteine-rich peptides, ncr343 and ncr-new35 are required for the maintenance of rhizobia in nitrogen-fixing nodules. new phytol. 2023 jun 28. doi: 10.1111/nph.19097. epub ahead of print. pmid: 37381081.

5.         li, pei, shen, rui zhang, mingming kang, yelin ma, dengyao li, yuhui chen*. progress in the self-regulation system in legume nodule development-aon (autoregulation of nodulation). int.j. mol. sci.2022, 23, 6676. https://doi.org/10.3390/ijms23126676.

6.         李宇赫，裴 悦，沈怡彤，张 锐，王宜宜，王劭学，姚莉琦，李力涵，康明明，李登耀，陈玉辉*. 利用 crispr-cas9 编辑蒺藜苜蓿串联重复基因. 草业科学，2022，39（10）：1-11.

7.          chen y., chen r. (2022) fast neutron bombardment (fnb)-induced mutant resources in medicago truncatula. in: sinharoy s., kang y., benedito v. (eds) the medicago truncatula genome. compendium of plant genomes. springer, cham. https://doi.org/10.1007/978-3-030-90757-0_4.

8.         jiejun xi, siyuan huang, weijie liu, shu he, yuhui chen, xiuzhu sun, guoliang pei, jiang zhao, jingzhang, peizhi yang, tianming hu.enhancement by sodium on the growth of the xerophyte zygophyllum xanthoxylum is achieved by maintaining efficient photosynthesis when stomatal aperture is minimized. environmental and experimental botany. , november 2021, 104624 10.1016/j.envexpbot.2021.104624

9.         wang t, ren l, li c, zhang d, zhang x, zhou g, gao d, chen r, chen y, wang z, shi f, farmer ad, li y, zhou m, young nd, zhang wh. the genome of a wild medicago species provides insights into the tolerant mechanisms of legume forage to environmental stress. bmc biol. 2021 may 6;19(1):96. doi: 10.1186/s12915-021-01033-0.pmid: 33957908 free pmc article.  doi: 10.1186/s12915-021-01033-0

10.       chen, y., xi, j. and chen, r. (2019) medicago truncatula esn1, a key regulator of nodule development and symbiotic nitrogen fixation. in: the model legume medicago truncatula. ed. frans j. debruijn (wiley/blackwell).2019, dec, 13: 701-705. doi:10.1002/9781119409144.

11.       gyöngyi zs. kováts, lili fodor, beatrix horváth, ágota domonkos, gergely iski, yuhui chen, rujin chen and péter kaló (2019) isolation and characterization of the non-transposon symbiotic nitrogen fixing mutants of medicago truncatula. in: the model legume medicago truncatula. ed. frans j. debruijn (wiley/blackwell). 2019, dec, 13: 1006-1014. doi:10.1002/9781119409144.

12.      liu, j., rutten, l., limpens, e., van der molen, t., van velzen, r., chen, r., chen, y., geurts, r., kohlen, w., kulikova, o., bisseling t. (2019) a remote cis-regulatory region is required for nin expression in the pericycle to initiate nodule primordium formation in medicago truncatula. plant cell. 2019 jan;31(1):68-83. doi: 10.1105/tpc.18.00478. epub 2019 jan 4.

13. chen y., chen r.* (2018) physical mutagenesis in medicago truncatula using fast neutron bombardment (fnb) for symbiosis and developmental biology studies. in: cañas l., beltrán j. (eds) functional genomics in medicago truncatula. methods in molecular biology, 1822:61-69. doi: 10.1007/978-1-4939-8633-0_4. humana press, new york, ny

14. yuhui chen, xianfu wang, shuifei lu, shibo li, rujin chen. an array-based comparative genomic hybridization (cgh) platform for efficient detection of copy number variations (cnvs) in fast neutron induced medicago truncatula mutants. j vis exp. (jove), 2017 nov 8;(129). doi: 10.3791/56470.

15.      wang, tianzuo; zhang, xiuxiu; liu, min; chen, yuhui; chen, rujin; wen, jiangqi; mysore, kirankumar; zhang, wenhao. novel phosphate deficiency-responsive long non-coding rnas in a legume model plant medicago truncatula. j exp bot. 2017 dec 16;68(21-22):5937-5948. doi: 10.1093/jxb/erx384.

16.     minsoo kim, yuhui chen, jiejun xi, christopher waters, rujin chen and dong wang. an antimicrobial peptide essential for bacterial survival in the nitrogen-fixing symbiosis. proc natl acad sci u s a., 2015 dec 8; 112(49):15238-43.

17.     beatrix horvath , agota domonkos , attila kereszt , attila szucs , edit abraham , ferhan ayaydin , karoly boka , yuhui chen , rujin chen , jeremy d murray , michael k udvardi , eva kondorosi, peter kalo. loss of a single nodule-specific cysteine rich peptide, ncr169 abolishes symbiotic nitrogen fixation in the medicago truncatula dnf7 mutant. proc natl acad sci u s a., 2015 dec 8; 112(49):15232-7.

18.    jiejunxi, yuhui chen,jinnakashima, suo-minwang, and rujinchen. medicago truncatula esn1 defines a genetic locus involved in nodule senescence and symbiotic nitrogen fixation. molecular plant-microbe interactions (mpmi), 2013, 26(8):893-902.

19. lijie cui, huizhen peng, ran zhang, yuhui chen, lingxia zhao and kexuan tang. recombinant hhscfv-rc-rnase protein derived from transgenic tobacco acts as a bifunctional molecular complex against hepatocellular carcinoma. biotechnol appl biochem. 2012 sep-oct; 59(5):323-9.

20.      lijie cui, yuhui chen, guoan shen, lingxia zhao, kexuan tang. expression of bioactive thymosin alpha 1 (tα1) in marker-free transgenic lettuce (lactuca sativa). plant mol biol rep, 2011, 29: 466-472.

21.     jianghua chen, jianbin yu, liangfa ge, hongliang wang, ana berbel, yu liu, yuhui chen, guangming li, million tadege, jiangqi wen, viviane cosson, kirankumar s. mysore, pascal ratet, francisco madueño, guihua bai, and rujin chen. control of dissected leaf morphology by a cys(2)his(2) zinc finger transcription factor in the model legume medicago truncatula. proc natl acad sci u s a. 2010, 107(23):10754-10759.

22.    yuhui chen, lingxia zhao, lijie cui, et al. expression of thymosin α1 concatemer in transgenic tomato (solanum lycopersicum) fruits. biotechnology and applied biochemistry, 2009 apr; 52(pt4):303-312.

23.    yuhui chen, lingxia zhao, guoan shen, et al. expression and analysis of thymosin alpha 1 concatemer in escherichia coli. biotechnology and applied biochemistry, 2008 jan 1; 49(pt1):51-56.

24.    yuhui chen, lingxia zhao, lijie cui, kexuan tang. progress in transgenic plants producing pharmaceutical proteins. (2007) review of china agricultural science and technology, 9(5):36-44.

25.   yuhui chen, lingxia zhao, chai yourong, et al. the study of transformation of tomato with the verticillium dahliae resistance gene stve gene from solanum torvum swartz. (2008). acta horticulturae sinica. 2008, 35 (5): 693-700. (in chinese)

26.   hui zhang, lingxia zhao, yuhui chen, et al. expression of human coagulation factor ix in transgenic tomato. (2007) biotechnology and applied biochemistry, oct, 48(pt2):109-16.

27.   donghui liu, hongbin jin, yuhui chen, lijie cui et al. terpenoid indole alkaloids biosynthesis and metabolic engineering in catharanthus roseus l. g. don. (2007) journal of integrative plant biology, 49(7):961-74.

28.   guoyin kai, junfeng chen, li li, genyu zhou, lei zhang, yuhui chen, lingxia zhao. molecular cloning and characterization of a new cdna encoding hyoscyamine 6 β-hydroxylase from roots of anisodus acutangulus. (2007) journal of biochemistry and molecular biology, 40(5): 715-22.

29.      hongbin jin, donghui liu, kaijing zuo, yifu gong, zhiqi miao, yuhui chen, weiwei ren, xiaofen sun, & kexuan tang. molecular cloning and characterization of crmdr1, a novel mdr-type abc transporter gene from catharanthus roseus. (2007) dna sequence, 18(4):316-25.

30. hongbin jin, donghui liu, kaijing zuo, zhiqi miao, yuhui chen, xiaofen sun, & kexuan tang. plant abc transporters and their roles in the transmembrane transport of secondary metabolites. (2007) journal of agricultural science and technology, 9(3):32-37. (in chinese)

31.    yuhui chen, xiangyang xu, guiying li, jingfu li. the application of gene engineering on creating male sterility to vegetable. (2004) china biotechnology, 24(6):12-18. （in chinese）

32.    yuhui chen, xiangyang xu, jingfu li. review of advances in research of the male sterility in tomato.(2004) journal of northeast agriculture university, 35(2):129-134. (in chinese)

33.    yuhui chen, xiangyang xu, jingfu li. the application of transgenic technique in tomato breeding. (2004) molecular plant breeding, 2(1):133-138. (in chinese)

book chapter

         zhao lingixa, wang fu, li zhugang, chai yourong, kai guoyin, chen yuhui, cui lijie, meng fanjuan. (2012, nov) “wild tomato resource (in chinese)”, shanghai jiao tong university press.